Vitamin D and cardiovascular disease – Have we found the answers?
نویسندگان
چکیده
منابع مشابه
Vitamin D and cardiovascular disease.
Vitamin D plays a classical hormonal role in skeletal health by regulating calcium and phosphorus metabolism. Vitamin D metabolites also have physiological functions in nonskeletal tissues, where local synthesis influences regulatory pathways via paracrine and autocrine mechanisms. The active metabolite of vitamin D, 1α,25-dihydroxyvitamin D, binds to the vitamin D receptor that regulates numer...
متن کاملVitamin D and cardiovascular disease.
The hormonal derivative of vitamin D, 1,25-dihydroxyvitamin D (1,25[OH](2)D) or calcitriol, has been implicated in many physiologic processes beyond calcium and phosphorus homeostasis, and likely plays a role in several chronic disease states, in particular, cardiovascular disease. Experimental data suggest that 1,25(OH)(2)D affects cardiac muscle directly, controls parathyroid hormone secretio...
متن کاملVitamin D and Cardiovascular Disease
Vitamin D insufficiency/deficiency has been observed worldwide at all stages of life. It has been characterized as a public health problem, since low concentrations of this vitamin have been linked to the pathogenesis of several chronic diseases. Several studies have suggested that vitamin D is involved in cardiovascular diseases and have provided evidence that it has a role in reducing cardiov...
متن کاملVitamin D and Cardiovascular Disease
Vitamin D is best known for its influence on skeletal health. There is growing recognition, however, that vitamin D has nonskeletal actions, which could have important implications for understanding the consequences of vitamin D deficiency. In epidemiologic studies, vitamin D deficiency has been consistently associated with an increased risk for cardiovascular disease and hypertension. Disrupti...
متن کاملVitamin D and Risk of Cardiovascular Disease.
Observational studies have mostly found a strong association of low plasma 25-hydroxyvitamin D (25(OH)D), usually used to measure vitamin D status, with increased risk of coronary heart disease, stroke, and cardiovascular death. However, recent Mendelian randomization studies and randomized intervention trials do not support a causal association of 25(OH)D or vitamin D supplementation with card...
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ژورنال
عنوان ژورنال: Indian Heart Journal
سال: 2015
ISSN: 0019-4832
DOI: 10.1016/j.ihj.2015.02.016